I’ve been playng for a while with ASP.NET AJAX Extensions. and I like it. Having studied Rails, I was missing some things I missed from Script.aculo.us so I tought that it was impossible no one would have used Script.aculo.us with ASP.NET. My collective memory (google) led me to this article: CoreWeb :: Script.aculo.us, Prototype and Asp.Net Best Friends Forever

I will check it out tonight and see what I can learn from that.